Asymmetric 13-dipolar cycloaddition of nitrones with ketene acetals catalyzed by chiral oxazaborolidines

Article abstract of DOI:10.1016/S0040-4039(00)73373-9

Asymmetric 1,3-dipolar cycloaddition of nitrones with ketene acetals is strongly catalyzed by chiral oxazaborolidines derived from N-tosyl-L-α-amino acids. The 5,5-dialkoxyisoxazolidines are obtained regioselectivity in high yield with high stereoselectiv