Aliphatic ethers and esters of 1-(2,4-dichlorophenyl)-2-(1H-imidazolyl)ethanol: study of antifungal activity against yeasts and hydrophobic character

Article abstract of DOI:10.1016/0223-5234(94)90032-9

Aliphate ethers 2 and esters 3, which are closely related to antifungal azoles, were synthesized and tested against various strains of Candida.We found that their activity was strongly related to the length of the chains; the best activity was obtained wi