Regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles by 1,3-dipolar cycloaddition: Role of Er(OTf)3, ionic liquid and water

DOI: 10.1016/j.tetlet.2019.01.053

Source and publish data:

Tetrahedron Letters p. 672 - 674 (2019)

Update date:2022-09-26

Topics:

Authors:

Maiuolo, Loredana

Russo, Beatrice

Algieri, Vincenzo

Nardi, Monica

Di Gioia, Maria Luisa

Tallarida, Matteo Antonio

De Nino, Antonio

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Article abstract of DOI:10.1016/j.tetlet.2019.01.053

A simple procedure to obtain 1,5-disubstituted 1,2,3-triazoles, using the Er(OTf)₃/[mpy]OTf/H₂O catalytic system is described. The reaction proceeds through an eliminative azide–olefin cycloaddition (EAOC) offering a highly regiosele

Full text of DOI:10.1016/j.tetlet.2019.01.053

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