The Knoevenagel Reactions of Aldehydes with Carboxy Compounds. I. Reactions of p-Nitrobenzaldehyde with Active Methine Compounds

DOI: 10.1246/bcsj.61.2473

Source and publish data:

Bulletin of the Chemical Society of Japan p. 2473 - 2480 (1988)

Update date:2022-08-05

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Authors:

Tanaka, Mayumi

Oota, Osamu

Hiramatsu, Hideo

Fujiwara, Kazuyoshi

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Article abstract of DOI:10.1246/bcsj.61.2473

The Knoenvenagel reactions of p-nitrobenzaldehyde (1) with β-keto acids, methylmalonic (2a) and α-methylacetoacetic acids (2b) were carried out in the presence of a tertiary amine such as pyridine.We have isolated the corresponding β-hydroxy intermediate

Full text of DOI:10.1246/bcsj.61.2473

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