Journal of the Chemical Society. Perkin transactions I p. 2451 - 2455 (1981)
Update date:2022-08-05
Topics:
Reese, Colin B.
Titmas, Richard C.
Valente, Lydia
When 5'-O-methoxytetrahydropyranylthymidylyl-(3' -> 5')-3'-O-methoxytetrahydropyranylthymidine o-chlorophenyl ester (12) is treated with an excess of toluene-p-thiol and triethylamine in acetonitrile solution at room temperature, it is cleaved to give 5'-O-methoxytetrahydropyranylthymidine 3'-(o-chlorophenyl) phosphate (10) and 5'-deoxy-5'-(p-tolylthio)-3'-O-methoxytetrahydropyranylthymidine (13).The bearing of this result on the synthesis of oligonucleotides by the phosphotriester approach is discussed.
View MoreShuanghe Bio-Technology Limited(expird)
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Wuhan Chemchemical Co., Ltd.(expird)
Contact:15973022782
Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.
Suzhou Health Chemicals Co., Ltd.
website:http://www.healthchems.com
Contact:13776257979
Address:No. 338, Jingang Avenue,
Nanjing Raise Pharmatech Co., Ltd
website:http://www.raisechem.com
Contact:+86-25-58649566
Address:B381,No.606,Ningliu Road,Jiangbei New Area,Nanjing,Jiangsu Province,China
Contact:+86-13666670345
Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
Doi:10.1002/hlca.19780610737
(1978)Doi:10.1021/jm00230a001
(1976)Doi:10.1002/jps.2600671111
(1978)Doi:10.1246/bcsj.51.3359
(1978)Doi:10.1016/S0040-4039(01)94908-1
(1978)Doi:10.1248/cpb.26.3450
(1978)
