Journal of Medicinal Chemistry p. 278 - 280 (1983)
Update date:2022-08-02
Topics:
Lee, Cheuk-Man
Zaugg, Harold E.
Michaels, Raymond J.
Dren, Anthony T.
Plotnikoff, Nicholas P.
Young, Patrick R.
Pursuit of the hypothesis that optimum central nervous system (CNS) activity in 2-azacannabinoids (I and II) requires a moderately basic nitrogen atom (pK = 5-7) has led to several very active α-amino amide derivatives, namely, 10-hydroxy-N,5,5-trimethyl-
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