Thiophene systems. 5. Thieno[3,4 b][1,5]benzoxazepines, thieno[3,4 b][1,5]benzothiazepines, and thieno[3,4 b][1,4]benzodiazepines as potential central nervous system agents

Article abstract of DOI:10.1021/jm00134a006

10-(Alkylamino)thieno[3,4-b][1,5]benzoxazepines (3) and 10-(alkylamino)thieno[3,4 b][1,5]benzothiazepines (4) were prepared by derivatization of the respective lactams (7 and 8) via phosphorus pentachloride and subsequent condensation with the appropriate