A deblocking method using thioether-sulfonic acid systems. Application to the synthesis of met-enkephalin

DOI: 10.1248/cpb.27.1472

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1472 - 1475 (1979)

Update date:2022-07-29

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Authors:

Kiso Kiso

Ito Ito

Nakamura

et al. et al.

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Article abstract of DOI:10.1248/cpb.27.1472

Thioanisole-trifluoromethanesulfonic acid and thioanisole-methanesulfonic acid systems were found to be useful as deblocking methods in the synthesis of a methionine-containing peptide, Met-enkephalin, without any side reaction.

Full text of DOI:10.1248/cpb.27.1472

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