Helvetica Chimica Acta p. 1937 - 1943 (1987)
Update date:2022-08-04
Topics:
Zuercher, Alois
Hesse, Manfred
Oxidation of the title compound 1 with KMnO4 under neutral condiitons led to the corresponding acid 2, 5-(2,3,4,5-tetrahydro-2-nitro-5-oxo-2-furyl)pentanoic acid (4), and 4-oxononadioic acid (6).On the basis of experimental results the mechanism of the formation of 4 is discussed (Scheme 1).Oxidation of 1 with KMnO4 under basic conditions gave 6 which was transformed to (E)-4,5-dihydro-5-(2'-oxocyclopentyliden)furan-2(3H)-one (12) with benzene/TsOH (Scheme 3).In contrast to this result the corresponding 4-oxoheptandioic acid (22) yields 1,6-dioxaspiro<4.4>nonan-2,7-dione (23) only (Scheme 4).
View MoreDisynthesis Chemical Technology Co. Ltd.
Contact:+86-571-88194596
Address:Dengyun road 380, Gongshu district, Hangzhou city, China
JIAXING SUNS INTERNATIONAL TRADE CO LTD
Contact:18367306858
Address:No.123,Huixin Avenue,Huimin Dist
Contact:+86+21-58956006 15800617331
Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai
Jinan Jinguilin Chemical Co.,Ltd
Contact:+86-531-81188412
Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
Yicheng Goto Pharmaceuticals Co.,Ltd.
Contact:+86 710 3423122
Address:5th Floor,East Gate of Building #2,Servo-Industrial Park,1st Qilin Road,Xiangyang,Hubei,China
Doi:10.1007/s10562-015-1515-6
(2015)Doi:10.1002/jlac.198119810310
(1981)Doi:10.1016/j.bmcl.2018.06.019
(2018)Doi:10.1021/jo01291a034
(1980)Doi:10.1021/ja00516a035
(1979)Doi:10.1021/om049866u
(2004)
