Design and reactivity of organic functional groups - Preparation and nucleophilic displacement reactions of imidazole-1-sulfonates (imidazylates)

Article abstract of DOI:10.1016/0040-4020(96)00586-8

Imidazole-1-sulfonate, a new type of leaving group by remote activation, allows facile S(N)2 substitution reactions at sterically crowded centers with various nucleophiles under mild conditions. It could be easily prepared from alcohols with cheap reagent