Journal of Medicinal Chemistry p. 238 - 240 (1978)
Update date:2022-08-02
Topics:
Mazzocchi
Harrison
1,2,3,4,5,6-Hexahydro-1,6-methano-3-benzazocine has been synthesized via a four-step sequence from benzonorbornadiene. This compound and its N-methyl derivative are more active than codeine in the mouse hot-plate antinociceptive assay and will not support morphine dependence in Rhesus monkeys.
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