Tricyclics with analgesic and antidepressant activity. 2. [[(Alkylamino)ethyl]thio]dibenzo[b,f]thiepins and 10,11-dihydro derivatives

DOI: 10.1021/jm00352a010

Source and publish data:

Journal of Medicinal Chemistry p. 1150 - 1153 (1982)

Update date:2022-08-05

Topics:

Authors:

Ong Ong

Profitt Profitt

Anderson

Spaulding

Wilker Wilker

Geyer III

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00352a010

A series of [[(alkylamino)ethyl]thio]dibenz[b,f]thiepins (III) and their 10,11-dihydro derivatives (IV) was synthesized and subjected to broad analgesic/CNS screening. Preliminary results indicated a combination of analgesic/anti-depressant profiles, simi

Full text of DOI:10.1021/jm00352a010

Products guided by the article

Product name:2-chloro-11-[β-(N-methyl-N-phenoxycarbonylamino)ethylthio]dibenzo[b,f]thiepin

Cas No:72291-46-4

R&D Labs maybe for 72291-46-4

HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
XZL BIO-TECHNOLOGY CO., LTD.

Contact:0086 533 2282832

Address:Zibo，Shandong
Shanghai Sharing technologies Co., Ltd.

Contact:86-021-66787223

Address:No11, Lane 225, Jinxiang Road,Pudong district
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province
Shandong Topscience Biotech Co., Ltd.

Contact:0633-2619278

Address:No. 98 Lanshan West Road, Lanshan District, Rizhao, Shandong Province, P.R. of China

Relevant to this article

Efficient and chemoselective direct reductive amination of aromatic aldehydes catalyzed by oxo-rhenium complexes containing heterocyclic ligands

Doi:10.1016/j.tet.2013.08.016
(2013)
Heterogeneous viologen catalysts for metal-free and selective oxidations

Doi:10.1039/c8gc03772h
(2019)
Synthesis of a staurosporine analogue possessing a 7-azaindole unit instead of an indole moiety

Doi:10.1016/j.tetlet.2004.04.102
(2004)
Physicochemical studies on some metal chelates of cyclodiphosphazane and thiourea monophosphazene derivatives

Doi:10.1080/10426500701501417
(2007)
1,3,5-tris(hydrogensulfato) benzene: A new and efficient catalyst for synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ol) derivatives

Doi:10.1016/S1872-2067(11)60477-4
(2012)
Electrophilic Addition of Benzeneselenenyl Chloride to Hydroxyalkynes

Doi:10.1021/jo01295a031
(1980)

Article Doi