Novel tetracyclic spiropiperidines. 1. 3-Aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidines] as potential antidepressants

DOI: 10.1021/jm00133a016

Source and publish data:

Journal of Medicinal Chemistry p. 74 - 79 (1981)

Update date:2022-09-26

Topics:

Authors:

Ong Ong

Profitt Profitt

Anderson

Kruse Kruse

Wilker Wilker

Geyer III

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Article abstract of DOI:10.1021/jm00133a016

A series of 3-aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidine] derivatives was synthesized and evaluated pharmacologically for potential psychotropic activity. Potent antidepressant-like activity was noted throughout the series, as assessed by tet

Full text of DOI:10.1021/jm00133a016

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