Journal of Medicinal Chemistry p. 333 - 335 (1980)
Update date:2022-08-02
Topics:
Elliott, Arthur J.
Eisenstein, Norman
Iorio, Louis C.
A number of 7-substituted 1-azaphenoxathiins and their sulfone oxidation products have been synthesized and screened for central nervous system activity.Some of the compounds have antidepressant activity, with the most active 7-(trifluoromethyl)-1-azaphenoxathiin 10,10-dioxide (8), having similar potency to imipramine.
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