Production of 13(S)-hydroperoxy-9(Z),11(E)-octadecadienoic acid using soybean lipoxygenase 1 in a biphasic octane-water system

Article abstract of DOI:10.1016/S0040-4039(00)76703-7

The synthetic potential of soybean lipoxygenase 1 (LOX 1) for the synthesis of 13(S) hydroperoxy-9(Z),11(E)-octadecadienoic acid is investigated in a biphasic medium (octane; borate buffer, pH 9.6). Improvement of the reaction yield (compared to an aqueous system) is observed at very high concentration (20-40 g/L). The regioselectivity of the reaction is not affected by the presence of the organic phase.