PHOSPHORYLATION OF NUCLEOSIDES USING MOLECULAR SIEVES AS ACID SCAVENGERS

DOI: 10.1016/S0040-4039(01)85538-6

Source and publish data:

Tetrahedron Letters p. 501 - 502 (1980)

Update date:2022-08-03

Topics:

Authors:

Kohli, V.

Bloecker, H.

Koester, H.

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Article abstract of DOI:10.1016/S0040-4039(01)85538-6

Molecular sieves (4 Angstroem) were used effectively to trap the generated hydrogen chloride during phosphorylation of protected nucleosides using phosphomonochloridates, thus preventing side reactions.

Full text of DOI:10.1016/S0040-4039(01)85538-6

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