Synlett p. 193 - 194 (1997)
Update date:2022-08-05
Topics:
Mahler, Mikael E.
Palmer, Michael J.
The novel trans-3-oxabicyclo[3,3.0]octan-7-one system has been prepared by intramolecular ring closure of the corresponding cyclopentane diol. Peralkylation and benzylidene substitution of the octanone has allowed the preparation of tetra-alkylated potential inhibitors of HIV protease. Weak activity against HIV protease (IC50's 70-100μM) was observed.
View MoreShanghai Kangxin Chemical Co., Ltd
Contact:+86 21 60717227
Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai
Changsha Nutritopper Bio Technology Co.,Ltd.
Contact:+86-731-87803543
Address:East 1st Street, Baima Road, Ningxiang County
Shaanxi King Stone Enterprise Company Limited
Contact:86-29-88353805,13609285751
Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Shanghai Yudiao Chemistry Technology Co.,Ltd
Contact:0086-18964703211
Address:Building NO.5, NO.218,Rongtian Road,ganxiang town,Jinshan District,shanghai,201518,china
Contact:+86-25-83719363
Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Doi:10.1055/s-2004-822389
(2004)Doi:10.1021/ja048587v
(2004)Doi:10.1139/v56-002
(1956)Doi:10.1021/jo901347u
(2009)Doi:10.1021/ja01555a048
(1958)Doi:10.1039/c39800000281
(1980)
