
Tetrahedron Asymmetry p. 859 - 862 (1997)
Update date:2022-08-02
Topics:
Suginome, Michinori
Iwanami, Taisuke
Matsumoto, Akira
Yoshihiko, Ito
Highly enantio-enriched (E)-allylsilanes, were synthesized by palladium-catalyzed intramolecular bis-silylation of chiral allyl alcohols and subsequent Peterson-type elimination with organolithium reagents, The enantiomeric excesses of the allylsilanes were determined after hydroboration with 9-BBN followed by oxidation, revealing remarkably high stereospecificity for the present synthesis.
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