PYRROLOINDOLES. 2. SOME ELECTROPHILIC SUBSTITUTION REACTIONS IN THE 1H,6H-PYRROLOINDOLE SERIES

Article abstract of DOI:10.1007/BF00561347

As expected, the 3 and 8 positions are the reaction centers of 1H,6H-pyrrolo<2,3-e>indole in the Vilsmeier-Haack and Mannich reactions.Diazo coupling takes place primarily in the 3 position and leads primarily to monosubstitution products. 6,8-Diacetyl-1H,6H-pyrrolo<2,3-e>indole and 1,8-diacetyl-1H,6H-pyrrolo<2,3-e>indole were isoleted from the acetylation products.