Journal of Organic Chemistry p. 3457 - 3462 (1985)
Update date:2022-09-26
Topics:
Bernardo, Silvano De
Tengi, John P.
Sasso, Gino J.
Weigele, Manfred
Clavalanine (Ro 22-5417), a new β-lactam antibiotic, 3-<(3S,5S(-7-oxo-1-aza-4-oxabicyclo<3.2.0>hept-3-yl>-L-alanine (1), was synthesized by a route in which D-xylose (4) supplied the stereochemical requirements.From 4 was elaborated a (2S,4S)-2-amino-4,5-
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(1980)
