New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4- (biphenylylmethoxy)quinoline derivatives

DOI: 10.1021/jm00100a007

Source and publish data:

Journal of Medicinal Chemistry p. 4027 - 4038 (1992)

Update date:2022-08-03

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Authors:

Bradbury

Allott Allott

Dennis Dennis

Fisher Fisher

Major Major

Masek Masek

Oldham Oldham

Pearce Pearce

Rankine Rankine

Revill Revill

Roberts Roberts

Russell Russell

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Article abstract of DOI:10.1021/jm00100a007

A novel series of nonpeptidic angiotensin II (AII) receptor antagonists is reported, derived from linkage of the biphenylcarboxylic acid or biphenylyltetrazole moiety found in previously described antagonists via a methyleneoxy chain to the 4-position of

Full text of DOI:10.1021/jm00100a007

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