Steroids p. 265 - 272 (1980)
Update date:2022-08-05
Topics:
Formstecher, P.
Lustenberger, P.
Dautrevaux, M.
Several 17β-carboxamide derivatives of natural and fluorinated glucocorticoids have been synthesized.The 17β-carboxylic derivatives were obtained by periodic acid oxidation of their side chains.They were then activated by N-hydroxybenzotriazole (HOBT) and coupled to several primary amines.Using this method eleven 17β-carboxamide derivatives have been prepared in good yields.
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Doi:10.1016/0040-4020(80)87027-X
(1980)Doi:10.1021/ic049585e
(2004)Doi:10.1016/j.ica.2013.11.030
(2014)Doi:10.1002/ejic.200300962
(2004)Doi:10.1039/c8ob01146j
(2018)Doi:10.1021/ja00310a075
(1985)
