Photochemical Syntheses of 1,2-Diazepines. 11. Regiospecific Synthesis of 1,2-Dihydro-1,2-diazepin-3-ones

Article abstract of DOI:10.1021/jo01313a016

Starting from 2-chloropyridine 7, a series of 1,2-diazepin-3-ones 16 was prepared by a five-step synthesis.The key intermediates were the bicyclic oxadiazolium salts 10 which led, through a methoxide ion induced ring opening, to the expected 2-methoxypyri