Inorganic Chemistry p. 1629 - 1632 (1981)
Update date:2022-07-30
Topics:
Davison, Alan
Jones, Alun G.
Orvig, Chris
Sohn, Miriam
The benzoyl-protected dimercaptodiamides (PhCOS(CH2)nCONH)2X (n = 1, X = (CH2)2, (CH2)3, and o-C6H4; n = 2, X = (CH2)2 and (CH2)3) have been synthesized. From these, via the sodium dithionite reduction of TcO4- in base, the technetium complexes [TcO(S(CH2)nCONXNCO(CH2)nS)] - (n = 1, X = (CH2)2, (CH2)3, and o-C6H4; n = 2, X = (CH2)2) have been prepared. The synthesis and characterization of the complexes, and their precursors, are presented, and the radiopharmaceutical applicability is discussed.
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(2012)
