Synthesis of thromboxane B3 and its direct separation from thromboxane B2 by reversed-phase high performance liquid chromatography

DOI: 10.1248/cpb.41.1769

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1769 - 1773 (1993)

Update date:2022-07-30

Topics:

Authors:

Nakamura

Nagai Nagai

Yoneda Yoneda

Suga Suga

Kawamura

Iguchi Iguchi

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Article abstract of DOI:10.1248/cpb.41.1769

The first chemical synthesis of thromboxane B₃ starting with the Corey lactone is described. A reversed-phase high-performance liquid chromatographic method was developed for the direct determination without derivatization, of thromboxane B₃ in the presence of thromboxane B₂.

Full text of DOI:10.1248/cpb.41.1769

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