Novel tetracyclic spiropiperidines. IV. Synthesis and pharmacological evaluation of spiro- and 6,7-dihydrospiro[benzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine-2(1H),4'- piperidine]s

DOI: 10.1021/jm00367a017

Source and publish data:

Journal of Medicinal Chemistry p. 81 - 83 (1984)

Update date:2022-08-04

Topics:

Authors:

Glamkowski

Fortunato

Ong Ong

Allen Allen

Wilker Wilker

Geyer III

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Article abstract of DOI:10.1021/jm00367a017

A previously described series of 1-arylspiro[indoline-3,4'-piperidine]s was reported by us to possess significant antidepressant properties. This biological activity was found to be at a maximum among those compounds bearing an ortho substituent (e.g., NH

Full text of DOI:10.1021/jm00367a017

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