SYNTHESES OF 4-ALKYLINDOLES FROM 2-METHYL-5-NITROISOQUINOLINIUM IODIDE

DOI: 10.1246/cl.1980.813

Source and publish data:

Chemistry Letters p. 813 - 816 (1980)

Update date:2022-08-04

Topics: Alkylation Catalyst Isolation Nucleophile Syntheses Reaction Mechanism Experimental conditions

Authors:

Somei, Masanori

Karasawa, Yoshio

Kaneko, Chikara

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Article abstract of DOI:10.1246/cl.1980.813

4-aminomethylindole was prepared economically on a large scale from 2-methyl-5-nitrosoisoquinolinium iodide.Subsequent alkaline hydrolysis afforded 4-methylaminomethylindole.Starting from these two compounds, various 3,4-di- and 4-subst

Full text of DOI:10.1246/cl.1980.813

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