Journal of Medicinal Chemistry p. 1745 - 1747 (1985)
Update date:2022-08-05
Topics:
Kukla, Michael J.
Breslin, Henry J.
Bowden, Charles R.
All four possible stereoisomers of cyclo(histidylproline) were individually synthesized, purified, and characterized.They were each tested for anoretic activity in rats with a free feeding paradigm over 24 h.Contrary to literature reports, none significantly reduced food intake at any time over the test period.
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