
Bioorganic and Medicinal Chemistry Letters p. 59 - 62 (2004)
Update date:2022-08-05
Topics:
East, Stephen P.
Beckett, R. Paul
Brookings, Daniel C.
Clements, John M.
Doel, Sheila
Keavey, Kenneth
Pain, Gilles
Smith, Helen K.
Thomas, Wayne
Thompson, Alison J.
Todd, Richard S.
Whittaker, Mark
A series of analogues of the peptide deformylase (PDF) inhibitor BB-3497 where the P3′ amide bond was replaced with a ketone functionality is described. The in vitro antibacterial profiling of these compounds revealed that they demonstrate activity agains
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