Reactions of Halogenomethanes in the Vapor Phase. Part 4. The Reactions of Imidazoles with Chloroform at 550 deg C, and a Comparison with their Liquid-phase Reactions with Trichloroacetate Ion or Hexachloroacetone and Base

DOI: 10.1039/P19800001427

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 1427 - 1430 (1980)

Update date:2022-08-02

Topics:

Authors:

Busby, Reginald E.

Khan, Mohammad A.

Khan, Mohammad R.

Parrick, John

Shaw, C. J. Granville

Iqbal, Mohammad

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/P19800001427

1-Unsubstituted imidazoles and chloroform at 550 deg C in a flow system give mainly 5-chloropyrimidines, together with 4-chloropyrimidines and chloropyrazines.The effects of methyl substituents on the ratio of products is considered.The liquid-phase reactions of 2-methyl- and 2,4,5-trimethyl-imidazole under conditions in which dichlorocarbene is said to be formed in basic or neutral conditions were studied, and compared with the gas-phase reactions with chloroform.

Full text of DOI:10.1039/P19800001427

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:Pyrimidine, 5-chloro-4,6-dimethyl- (9CI)

Cas No:75712-75-3

R&D Labs maybe for 75712-75-3

Nantong Kaixin Pharma Chemical Co.,Ltd.

Contact:86-513-85250786

Address:2-1103 Huachen Mansion, 111 Gongnong Road,Nantong, Jiangsu, China
Wuhan Konberd Biotech Co., Ltd.

Contact:+86-27-87205925

Address:NO.666, Gaoxin Road, Eastlake High-tech zone
Shandong Loyal Chemical industrial Co.,Ltd

Contact:0533-7451788

Address:Linzi Chemical Industrial Park, Zibo, Shandong Province
Valiant Fine Chemicals Co., Ltd.

Contact:+86 535 6101878/6374484

Address:11 Wuzhishan Rd.,YTETDZ,Yantai,264006,Shandong,China
Acros Pharmatech Limited

website:http://www.acrospharmatech.com

Contact:+1-3234804688

Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong

Relevant to this article

Antibacterial activity of some Garcinia benzophenone derivatives against methicillin-resistant Staphylococcus aureus

Doi:10.1248/bpb.19.311
(1996)
A NEW AND CONVENIENT ROUTE TO THE AMIDES OF α-AMINO ACIDS AND α-HYDROXY ACIDS BY MEANS OF THE PALLADIUM CATALYZED FACILE CLEAVAGE OF 3-SUBSTITUTED-4-ARYLAZETIDIN-2-ONES

Doi:10.1246/cl.1980.853
(1980)
Molecular Organization by Hydrogen Bonding: Juxtaposition of Remote Double Bonds for Photocyclization in a 2-Pyridone Dimer

Doi:10.1021/jo00316a027
(1981)
NEW BIS- AND TRIS-ANNULATION REAGENTS FOR THE SYNTHESIS OF CD RINGS OF STEROIDS, BEARING A FUNCTIONALIZED 18-METHYL GROUP, BY THE PALLADIUM CATALYZED CYCLIZATION

Doi:10.1016/S0040-4039(00)78697-7
(1980)
DIRECTION OF CARBONIUM ION REARRANGEMENTS DURING ACYLATION OF PROPYNE BY STEREOISOMERS OF 4-tert-BUTYL-1-METHYLCYCLOHEXANOYLCARBONYL CATION

Doi:10.1007/BF01168282
(1980)
SYNTHESIS OF ACETYLENYL-N-METHYLPYRROLES

Doi:10.1007/BF00950586
(1980)

Article Doi