
Journal of Fluorine Chemistry p. 51 - 62 (1980)
Update date:2022-07-30
Topics:
Paciorek, K. J. L.
Ito, T. I.
Nakahara, J. H.
Kaufman, J.
Kratzer, R. H.
Rosser, R. W.
Perfluoroalkylether amidoximes free from amide-contamination were prepared from imidate esters.The amidoximes were stable at 110 deg C; at ca. 170 deg C partial decomposition to 1,2,4-oxadiazoles, admixed with other compounds, took place.Interactions between nitriles and amidoximes at 50 deg C resulted in the formation of imidoylamidoximes; these dissociated readily into their constituents when subjected to higher temperatures.At 70 deg C and above, in the presence of excess nitrile or other ammonia acceptors, the imidoylamidoximes afforded high yields of the corresponding 1,2,4-oxadiazoles.
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