A NEW SYNTHETIC STRATEGY FOR HETEROANTHRACYCLINES: TOTAL SYNTHESIS OF D-RING THIOPHENE ANALOGS OF DAUNOMYCIN

DOI: 10.1016/S0040-4039(00)96434-7

Source and publish data:

Tetrahedron Letters p. 3971 - 3974 (1987)

Update date:2022-09-26

Topics:

Authors:

Tamura, Yasumitsu

Kirihara, Masayuki

Sekihachi, Jun-ichi

Okunaka, Ryuichi

Mohri, Shin-ichiro

et. al. et. al.

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Article abstract of DOI:10.1016/S0040-4039(00)96434-7

The strong base-induced cycloaddition of appropriately functionalized thiophene analogs of homophthalic anhydride constitutes a highly regiospecific and convenient route to the D-ring thiophene analogs (2 and 3) of daunomycin.

Full text of DOI:10.1016/S0040-4039(00)96434-7

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