A NEW SYNTHETIC STRATEGY FOR HETEROANTHRACYCLINES: TOTAL SYNTHESIS OF D-RING THIOPHENE ANALOGS OF DAUNOMYCIN

DOI: 10.1016/S0040-4039(00)96434-7

Source and publish data:

Tetrahedron Letters p. 3971 - 3974 (1987)

Update date:2022-09-26

Topics:

Authors:

Tamura, Yasumitsu

Kirihara, Masayuki

Sekihachi, Jun-ichi

Okunaka, Ryuichi

Mohri, Shin-ichiro

et. al. et. al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)96434-7

The strong base-induced cycloaddition of appropriately functionalized thiophene analogs of homophthalic anhydride constitutes a highly regiospecific and convenient route to the D-ring thiophene analogs (2 and 3) of daunomycin.

Full text of DOI:10.1016/S0040-4039(00)96434-7

Products guided by the article

Product name:4-Nitro-benzoic acid (2S,3S,4S,6S)-6-((6S,8S)-8-acetyl-5,8,10-trihydroxy-4,11-dioxo-4,6,7,8,9,11-hexahydro-anthra[2,3-b]thiophen-6-yloxy)-2-methyl-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yl ester

Cas No:76887-91-7

R&D Labs maybe for 76887-91-7

Shandong Xingshun New Material Co., Ltd.

website:http://www.sd-xingshun.com

Contact:+86-519-86461196

Address:Middle of Luhua East Road, Dingtao District
Second Pharma Co., Ltd

Contact:+86-575-82733999 0575-82732999

Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
Shanghai PotentPharm Science and Technology Co.,Ltd

Contact:86-021-51969655

Address:Unit B, Building 18, No.300, Chuantu Rd,Pudong District, Shanghai 201202, China
ShangHai Soyoung Biotechnology Inc

website:http://www.soyoungbio.com

Contact:+86-21-69893009

Address:shanghai
Shanghai Korey Pharm Co.,Ltd.(expird)

Contact:021-61840961 021-61840962

Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China

Relevant to this article

First Example of Electrophilic Substitution by Addition-Elimination (?-Substitution) in Pyrroles

Doi:10.1039/C39860001585
(1986)
Infrared spectroscopic detection of ketene formation from carbene and CO sources: an amide synthesis

Doi:10.1039/c9nj06161d
(2020)
Mild and practical stereoselective synthesis of (Z)- and (E)-allyl bromides from Baylis-Hillman adducts using Appel agents (PPh₃/CBr₄): a facile synthesis of semiplenamides C and E

Doi:10.1016/j.tetlet.2009.02.132
(2009)
Enantiomerically pure cyclopropane building blocks: Synthesis and transformations of 2-iodocyclopropylboronic esters

Doi:10.1002/adsc.200404055
(2004)
Metal-Free Intermolecular Azide-Alkyne Cycloaddition Promoted by Glycerol

Doi:10.1002/chem.201503858
(2015)
Electrocatalytic Oxidant-Free Dehydrogenative C?H/S?H Cross-Coupling

Doi:10.1002/anie.201700012
(2017)

Article Doi