A NEW SYNTHETIC STRATEGY FOR HETEROANTHRACYCLINES: TOTAL SYNTHESIS OF D-RING THIOPHENE ANALOGS OF DAUNOMYCIN

DOI: 10.1016/S0040-4039(00)96434-7

Source and publish data:

Tetrahedron Letters p. 3971 - 3974 (1987)

Update date:2022-09-26

Topics:

Authors:

Tamura, Yasumitsu

Kirihara, Masayuki

Sekihachi, Jun-ichi

Okunaka, Ryuichi

Mohri, Shin-ichiro

et. al. et. al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)96434-7

The strong base-induced cycloaddition of appropriately functionalized thiophene analogs of homophthalic anhydride constitutes a highly regiospecific and convenient route to the D-ring thiophene analogs (2 and 3) of daunomycin.

Full text of DOI:10.1016/S0040-4039(00)96434-7

Products guided by the article

Product name:4-Nitro-benzoic acid (2S,3S,4S,6S)-6-((6S,8S)-8-acetyl-5,8,10-trihydroxy-4,11-dioxo-4,6,7,8,9,11-hexahydro-anthra[2,3-b]thiophen-6-yloxy)-2-methyl-4-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-3-yl ester

Cas No:76887-91-7

R&D Labs maybe for 76887-91-7

Luna Chemicals Co.,Ltd.

Contact:+86-570-4336358

Address:No.87 Building,Tianqian,Sidu Town
SJZ Chenghui Chemical Co., Ltd.

Contact:86-311-87713916

Address:no.368 youyi north avenue
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
HK Vast Medicinal Chemistry Int'l Group Limited(expird)

website:http://www.hkvast.com/

Contact:+86-15000309979

Address:NO.6,Lane 108,Qinzhou Road,Xuhui District,Shanghai
Hebei DaPeng Pharm & Chem Co., Ltd.

Contact:86-317-7298678,0576-88861898 88861908

Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China

Relevant to this article

First Example of Electrophilic Substitution by Addition-Elimination (?-Substitution) in Pyrroles

Doi:10.1039/C39860001585
(1986)
Infrared spectroscopic detection of ketene formation from carbene and CO sources: an amide synthesis

Doi:10.1039/c9nj06161d
(2020)
Mild and practical stereoselective synthesis of (Z)- and (E)-allyl bromides from Baylis-Hillman adducts using Appel agents (PPh₃/CBr₄): a facile synthesis of semiplenamides C and E

Doi:10.1016/j.tetlet.2009.02.132
(2009)
Enantiomerically pure cyclopropane building blocks: Synthesis and transformations of 2-iodocyclopropylboronic esters

Doi:10.1002/adsc.200404055
(2004)
Metal-Free Intermolecular Azide-Alkyne Cycloaddition Promoted by Glycerol

Doi:10.1002/chem.201503858
(2015)
Electrocatalytic Oxidant-Free Dehydrogenative C?H/S?H Cross-Coupling

Doi:10.1002/anie.201700012
(2017)

Article Doi