Tetrahedron p. 1847 - 1850 (1980)
Update date:2022-08-06
Topics:
Burger
Chen
De Waard
Huisman
Lithiation of the sulfones 1-3 in THF at -78° with lithium diisopropyl amide (LDA) is regioselective, since deuteration of the α-lithiosulfone 4 results in formation of the α-monodeuteriated sulfone 7. Higher temperature causes an intramolecular 1,4-addit
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