A convenient method for the selective reduction of amides to amines

DOI: 10.1016/0040-4039(80)88066-X

Source and publish data:

Tetrahedron Letters p. 4061 - 4064 (1980)

Update date:2022-08-04

Topics:

Authors:

Raucher, Stanley

Klein, Peter

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Article abstract of DOI:10.1016/0040-4039(80)88066-X

A variety of amides have been selectively reduced to the corresponding amines via conversion to their thioamides and treatment with triethyloxonium tetrafluoroborate followed by sodium borohydride. This procedure is compatible with isolated and conjugated double bonds, esters, intro groups, and sulfonamides.

Full text of DOI:10.1016/0040-4039(80)88066-X

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