A convenient method for the selective reduction of amides to amines

Article abstract of DOI:10.1016/0040-4039(80)88066-X

A variety of amides have been selectively reduced to the corresponding amines via conversion to their thioamides and treatment with triethyloxonium tetrafluoroborate followed by sodium borohydride. This procedure is compatible with isolated and conjugated double bonds, esters, intro groups, and sulfonamides.