Cyclic Urea Nucleosides. Cytidine Deaminase Activity as a Function of Aglycon Ring Size

DOI: 10.1021/jm00138a003

Source and publish data:

Journal of Medicinal Chemistry p. 662 - 666 (1981)

Update date:2022-08-04

Topics:

Authors:

Liu, Paul S.

Marquez, Victor E.

Driscoll, John S.

Fuller, Richard W.

McCormack, John J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00138a003

Five β-D-ribofuranosyl cyclic urea nucleosides (14-18), ranging in size from five to eight membered, were synthesized and evaluated as cytidine deaminase (CDA) inhibitors.The precursor protected nucleosides (9-13) were prepared by a condensation procedure

Full text of DOI:10.1021/jm00138a003

Products guided by the article

Product name:C₂₉H₂₆N₂O₈

Cas No:77273-79-1

R&D Labs maybe for 77273-79-1

SHIFANG SUHONG CHEMICAL CO.,LTD

Contact:+86-838-2224563

Address:Room 1207 Zongchen Sunshine No.128 Taishan South Road,Deyang City,Sichuan China
Beijing Zhongshuo Pharmaceutical T & D Co.,Ltd

Contact:0086-10-64430626

Address:ea No 16, HEPINGLI,DONGCHENG DISTRICT,BEIJING,P.R.CHINA.
HAORUI ENTERPRISES LLC

Contact:(1) 206-3550089

Address:5115 NE 8TH PL, Renton, WA 98059 USA
Jiangsu Institute of Ecomones Co., Ltd

website:http://www.jsmone.com

Contact:+86-519-82821700

Address:95 Huanyuan N. Road, Jintan, Jiangsu, China
Suzhou Time-chem Technologies Co., Ltd.

Contact:0512-63983931/68086856

Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China

Relevant to this article

Thermolysis of Polyazapentadienes. Part 11. Concerted and Free Radical Mechanisms in 2-Aza Enone and 2-Aza Enthione Pyrolyses: Crystal and Molecular Structures of 3-Dimethylamino-1-p-tolyl-2-azaprop-2-en-1-one and 3-Dimethylamino-1-phenyl-2-azaprop-2-ene-1-thione

Doi:10.1039/P19890000589
(1989)
Doi:10.1007/BF00846079
()
Structure of octa-O-acetyl-tris(N-ethoxycarbonyl)destomycin A

Doi:10.1246/bcsj.54.2147
(1981)
Electron Spin Resonance Studies. Part 58. The Formation and Reactions of Some Aliphatic Radical-cations in Aqueous Solution

Doi:10.1039/P29800000647
(1980)
The Acid-catalyzed Reaction of the 2-Oxabicyclo<4.1.0>hept-3-en-5-one System: Isomerization from Homo-4-pyrones into 2-Furylacetone Derivatives

Doi:10.1246/bcsj.53.469
(1980)
Structural Modification on Partially Silylated Carbohydrates by Means of Triphenylphosphane/Diethylazodicarboxylate. IV. Transformations on Mannose and Galactose

Doi:10.1007/BF00938735
(1980)

Article Doi