Cyclic Urea Nucleosides. Cytidine Deaminase Activity as a Function of Aglycon Ring Size

DOI: 10.1021/jm00138a003

Source and publish data:

Journal of Medicinal Chemistry p. 662 - 666 (1981)

Update date:2022-08-04

Topics:

Authors:

Liu, Paul S.

Marquez, Victor E.

Driscoll, John S.

Fuller, Richard W.

McCormack, John J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00138a003

Five β-D-ribofuranosyl cyclic urea nucleosides (14-18), ranging in size from five to eight membered, were synthesized and evaluated as cytidine deaminase (CDA) inhibitors.The precursor protected nucleosides (9-13) were prepared by a condensation procedure

Full text of DOI:10.1021/jm00138a003

Products guided by the article

Product name:C₂₉H₂₆N₂O₈

Cas No:77273-79-1

R&D Labs maybe for 77273-79-1

Shanghai Sungo Technology Chemical Co., Ltd

Contact:0086-21-51385579

Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Arshine Pharmaceutical Co., Limited

website:http://www.cnarshine.com

Contact:0731-88503671

Address:Room 1109.Block C3, Lugu Enterprise Plaza,No.27 Wenxuan Road,Changsha National Hi-Tech Industrial Development Zone,Hunan ,P.R.China
Guarson Chemical Co., Ltd.

website:http://www.guarson.com

Contact:+86-523-88059600,+86-13805268803

Address:Room B1006,Yafang Building,Jiangyan Avenue,Jiangyan District, Taizhou City,Jiangsu,China
Accendatech Co., LTD

Contact:+86-22-83718541

Address:32th Floor, Rongqiao Center Intersection of Changjiang Road and Nankai Six Road Nankai District Tianjin 300102, China
NEWSTAR CHEM ENTERPRISE LTD.

Contact:0572-2722882

Address:1201,F3,xinghuibandao,

Relevant to this article

Thermolysis of Polyazapentadienes. Part 11. Concerted and Free Radical Mechanisms in 2-Aza Enone and 2-Aza Enthione Pyrolyses: Crystal and Molecular Structures of 3-Dimethylamino-1-p-tolyl-2-azaprop-2-en-1-one and 3-Dimethylamino-1-phenyl-2-azaprop-2-ene-1-thione

Doi:10.1039/P19890000589
(1989)
Doi:10.1007/BF00846079
()
Structure of octa-O-acetyl-tris(N-ethoxycarbonyl)destomycin A

Doi:10.1246/bcsj.54.2147
(1981)
Electron Spin Resonance Studies. Part 58. The Formation and Reactions of Some Aliphatic Radical-cations in Aqueous Solution

Doi:10.1039/P29800000647
(1980)
The Acid-catalyzed Reaction of the 2-Oxabicyclo<4.1.0>hept-3-en-5-one System: Isomerization from Homo-4-pyrones into 2-Furylacetone Derivatives

Doi:10.1246/bcsj.53.469
(1980)
Structural Modification on Partially Silylated Carbohydrates by Means of Triphenylphosphane/Diethylazodicarboxylate. IV. Transformations on Mannose and Galactose

Doi:10.1007/BF00938735
(1980)

Article Doi