DIANION OF N-(o-METHOXYPHENYL)-2-METHYLPROPENAMIDE: A NEW REAGENT FOR THE CONVENIENT SYNTHESIS OF α-METHYLENE-γ-BUTYROLACTONES FROM CARBONYL COMPOUNDS

Article abstract of DOI:10.1246/cl.1980.1567

Dianion of N-(o-methoxyphenyl)-2-methylpropenamide was successfully generated on treatment of the amide with t-BuOK-BuLi at -78 degC in THF and utilized as the key reagent for the synthesis of γ-substituted α-methylene-γ-butyrolactones.