Bioorganic and Medicinal Chemistry Letters p. 2303 - 2308 (2004)
Update date:2022-08-05
Topics:
Gong, Baoqing
Hong, Feng
Kohm, Cory
Jenkins, Scott
Tulinsky, John
Bhatt, Rama
De Vries, Peter
Singer, Jack W.
Klein, Peter
2,4-Diamino-N4,6-diarylpyrimidines were identified as potent, isoform specific inhibitors of lysophosphatidic acid acyltransferase-β (LPAAT-β). Active inhibitors also blocked proliferation of tumor cell lines in vitro. The effect of 2j in an in
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