Total synthesis of the polyene macrolide roxaticin

DOI: 10.1016/S0040-4039(00)78257-8

Source and publish data:

Tetrahedron Letters p. 6503 - 6506 (1994)

Update date:2022-08-02

Topics:

Authors:

Mori, Yuji

Asai, Motoya

Kawade, Jun-Ichiro

Okumura, Akiko

Furukawa, Hiroshi

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Article abstract of DOI:10.1016/S0040-4039(00)78257-8

Roxaticin has been synthesized in a convergent manner. The polyol and polyene fragments were coupled by Horner-Emmons reaction and the cyclization was achieved by macrolactonization.

Full text of DOI:10.1016/S0040-4039(00)78257-8

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