ENANTIOSELECTIVE SYNTHESIS OF SILOXYCYCLOPROPANES AND OF γ-OXOCARBOXYLATES BY ASYMMETRIC CATALYSIS

Article abstract of DOI:10.1016/S0040-4039(01)93716-5

Up to 48percent enantiomeric excess have been attained by cyclopropanation of silyl enol ethers with methyl diazoacetate in the presence of optically active Cu-catalysts.Subsequent ring opening of resulting siloxycyclopropanes gives γ-oxocarboxylates with