
Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases p. 1405 - 1410 (1981)
Update date:2022-08-03
Topics:
Lahiri, Jyotirmay
Basu, Rama
The interaction of the antibiotic drugs tetracycline and oxytetracycline with purines, pyrimidines and amino acids were studied spectrophotometrically in water, ethylene glycol and propylene glycol.In each case a new absorption band was located and denoted as a charge-transfer band.The formation constants for the charge-transfer complexes were determined using Benesi-Hildebrand's method followed by an iterative procedure.Different linear plots for hν against the highest filled ?-molecular orbital of the donors (purines, pyrimidines and amino acids) were obtained indicating different stabilization energies for each system.
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