Journal of the Chemical Society. Perkin transactions I p. 1520 - 1530 (1981)
Update date:2022-07-29
Topics:
Meth-Cohn, Otto
Narine, Bramha
Tarnowski, Brian
Acetanilides are converted into 2-chloroquinoline-3-carbaldehydes in good yield by the action of Vilsmeier's reagent in phosphoryl chloride solution.The reaction is shown to involve successive conversion of the acetanilide into an imidoyl chloride and then an N-(α-chlorovinyl)aniline.The latter enamine is diformylated at its β-position and subsequently cyclised to the chloroquinolinecarbaldehyde.The diformylated intermediates may be isolated in several cases and separately cyclised with polyphosphoric acid.
View MoreVanderArk International Limited
Contact:86-10-82437576
Address:Qing He
SHANDONG CREDAGRI CHEMICAL CO., LTD.
Contact:+86-531-88872050
Address:ROOM 601A, BUILDING 2, SHUNTAI SQUARE, NO. 2000 SHUNHUA ROAD, HI-TECH DEVELOPMENT ZONE, JINAN, CHINA.
website:http://www.antimex.com
Contact:0086-21-50563169
Address:Room1027,No.Jinyu Road,Pudong
SEA BRGIHT INDUSTRY CO.,LIMITED
Contact:0086 755 8622 3990
Address:Rm 17B3,GuangCaiXinTianDi Bldg,GuiMiao Rd,NanShan District,Shenzhen,China
Contact:+86-574-89075960
Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
Doi:10.1039/c9cc04432a
(2019)Doi:10.1016/S0022-328X(00)81192-4
(1981)Doi:10.1055/s-1981-29450
(1981)Doi:10.1016/j.molcata.2007.01.031
(2007)Doi:10.1016/S0040-4039(01)93300-3
(1981)Doi:10.1021/j150614a028
(1981)
