Stereoselective synthesis of 2-(2'-cycloalkenyl) glycinates via [3,3] sigmatropic rearrangement of chelated ester-enolates

Article abstract of DOI:10.1016/S0040-4020(01)81208-4

Ester-enolate Claisen rearrangement of chelated N-protected cycloalkenyl glycinates 1 results in the formation of cyclic γ,δ-unsaturated amino acids in good yields and in a highly diastereoselective fashion.