Synthesis and Biological Properties of New Hexapeptide Substrates for Vitamin K Dependent Carboxylase. Evidence for X-Pro Cis/Trans Amide Bond Interconversions in Prothrombin Precursor Fragment 18-22

DOI: 10.1021/jm00360a023

Source and publish data:

Journal of Medicinal Chemistry p. 910 - 916 (1983)

Update date:2022-08-05

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Authors:

Rich, Daniel H.

Kawai, Megumi

Goodman, Hedda L.

Suttie, John W.

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Article abstract of DOI:10.1021/jm00360a023

Three hexapeptide analogues, corresponding to sequence 18-23 of bovine prothrombin precursor <> have been synthesized and evaluated as substrates for vitamin K dependent carboxylase.These new hexapeptides are moderately good substrates for the ca

Full text of DOI:10.1021/jm00360a023

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