Journal of the Chemical Society. Perkin transactions I p. 2751 - 2759 (1981)
Update date:2022-09-26
Topics:
Brownbridge, Peter
Egert, Ernst
Hunt, Paul G.
Kennard, Olga
Warren, Stuart
Alkylation of α-(phenylthio)-ketones or -esters with iodoacetate anion gives 1,4-dicarbonyl compounds which are reduced stereoselectively to β-phenylthio-γ-butyrolactones.Oxidation to sulphoxides and thermolysis provides a general synthesis of β- and γ-substituted Δαβ-butenolides.Treatment of 5,5-dimethyl-4-oxo-3-(phenylthio)-hexanoic acid with NaBH4 gives a single γ-lactone whose PhS and But groups are shown to be cis by X-ray crystal structure determination.
View MoreLaohekou Jinghong Chemical Co.,Ltd
Contact:+86-0710-3702747
Address:163.East，Huagong Road，Laohekou
Contact:+86-29-88710656
Address:South Tai bai Road, High Tech Development Zone, Xi'an China
Shanghai WinTide BioTechnology Co.,Ltd
Contact:86-21-37100630
Address:No. 908 Yunhe Road, Fengxian district, Shanghai
Shanghai Forever Synthesis Co.,Ltd.
Contact:021-61124658
Address:Zhoukang Road,Pudong New District,Shanghai,China
Taizhou YOJOY Chemical Co., Ltd.
Contact:13857143241
Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China
Doi:10.1021/acs.joc.9b00683
(2019)Doi:10.1016/S0008-6215(00)80526-1
(1981)Doi:10.1055/s-1982-29825
(1982)Doi:10.1021/jo00343a014
(1982)Doi:10.1007/s10593-008-0013-9
(2008)Doi:10.1016/S0040-4020(01)92542-6
(1966)
