Tetrahedron Letters p. 4819 - 4822 (1988)
Update date:2022-08-02
Topics:
Bell, Thomas W.
Hu, Lain-Yen
A one-pot approach to 6-membered heterocyclic rings combines two 1,3-dipole equivalents: 2-azaallyl anions(2) and iodosilane 3.The resulting cis-2,6-disubstituted 4-methylenepiperidines are converted in high yield to 2,4,6-trisubstituted pyridines (6) by oxidation with mercuric acetate in acetic acid.
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(1997)
