Journal of Pharmaceutical Sciences p. 1011 - 1014 (1981)
Update date:2022-08-05
Topics:
Uyeki
Nishio
Wittek
Cheng
A study of the antiproliferative activity of doxorubicin and several substituted aminoanthraquinone derivatives on Chinese hamster ovary cells was conducted. Doxorubicin and a derivative each inhibited cell prliferation at low concentrations, the latter being more potent than doxorubicin. A structure-activity relationship of these compounds is discussed in connection with an earlier postulated N-O-O triangulation hypothesis.
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Doi:10.1016/S0040-4020(01)97987-6
(1981)Doi:10.1016/S0040-4039(01)81958-4
(1981)Doi:10.1002/ejoc.201800263
(2018)Doi:10.1055/s-1981-29645
(1981)Doi:10.1021/jo00343a031
(1982)Doi:10.1055/s-2008-1072565
(2008)