PHOSPHOTRIESTER APPROACH TO OLIGOTHYMIDYLATE SYNTHESIS UTILIZING A SIMPLE THYMIDINE UNIT AND A NEW TYPE OF CONDENSING AGENT

DOI: 10.1016/S0040-4039(01)81865-7

Source and publish data:

Tetrahedron Letters p. 3209 - 3212 (1981)

Update date:2022-08-04

Topics:

Authors:

Sekine, Mitsuo

Matsuzaki, Jun-ichi

Hata, Tsujiaki

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Article abstract of DOI:10.1016/S0040-4039(01)81865-7

DMTrTp(SPh)2 was proposed as a simplest "nucleotide unit" for the synthesis of olygothymidylates.One phenylthio group was removed selectively and rapidly from dithiol-esters by 1M pyridinium hypophosphonate.Two kinds of arenedisulfonyl chlorides were newl

Full text of DOI:10.1016/S0040-4039(01)81865-7

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