Potential inhibitors of nucleotide biosynthesis. 2. Halomethyl ketone derivatives of pyrimidine nucleosides

DOI: 10.1021/jm00371a022

Source and publish data:

Journal of Medicinal Chemistry p. 680 - 684 (1984)

Update date:2022-08-03

Topics:

Authors:

Montgomery

Thomas Thomas

Brockman

Elliott Elliott

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Article abstract of DOI:10.1021/jm00371a022

Several halomethyl ketone derivatives of pyrimidine nucleosides have been prepared for evaluation as cytotoxic agents. The first series are 1-(8-halo-2,5,6,8-tetradeoxy-β-D-erythro-oct-7-ulofuranosyl)thymines, whereas the second type are halo derivatives

Full text of DOI:10.1021/jm00371a022

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