Potential inhibitors of nucleotide biosynthesis. 2. Halomethyl ketone derivatives of pyrimidine nucleosides

DOI: 10.1021/jm00371a022

Source and publish data:

Journal of Medicinal Chemistry p. 680 - 684 (1984)

Update date:2022-08-03

Topics:

Authors:

Montgomery

Thomas Thomas

Brockman

Elliott Elliott

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00371a022

Several halomethyl ketone derivatives of pyrimidine nucleosides have been prepared for evaluation as cytotoxic agents. The first series are 1-(8-halo-2,5,6,8-tetradeoxy-β-D-erythro-oct-7-ulofuranosyl)thymines, whereas the second type are halo derivatives

Full text of DOI:10.1021/jm00371a022

Products guided by the article

Product name:N-<4-<2-(chloromethyl)-1,3-dioxolan-2-yl>phenyl>-1,2-dideoxy-1-<3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl>-β-D-erythro-pentofuranuronamide

Cas No:80647-05-8

R&D Labs maybe for 80647-05-8

Tradlon Chemical Co., Ltd.

Contact:+86-710-3516804

Address:Number 83,Panggong road,Xiangcheng District,Xiangyang ,Hubei
CHEMINN LTD.

website:http://www.cheminn.com/

Contact:86-531-67875205

Address:No.9-2,South of Shanda Road, Jinan ,China
Beijing Wisdom Chemicals Co., Ltd.

Contact:+86-10-52350335

Address:F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
Shanghai Kefu Chemical Co.,Ltd.

Contact:+86-21-34616196

Address:Room601-602, Xuhui Business Building, No.168, Yude Road, Shanghai
Beyond Pharmaceutical Co., Ltd

Contact:+86-571-8195-3185

Address:No. 13-1, Liansheng Road, Yuhang District

Relevant to this article

Synthesis and NMR spectroscopic elucidation of four diastereoisomers of oxygenated bisabolane side chain

Doi:10.1002/hlca.201400395
(2015)
Synthesis of a digermane-containing tricylic nonadecadienedione incorporating an equivalent of ring-opened THF

Doi:10.1021/ic0491027
(2004)
Selective deprotection of phthalyl protected amines

Doi:10.1016/0040-4039(96)01752-2
(1996)
Doi:10.1139/v65-093
(1965)
Application of Regioselective Thiophene Lithiation to the Synthesis of Thiophene Analogues of Xanthones and Thioxanthones

Doi:10.1021/jo00348a032
(1982)
The facile synthesis of α-aryl-α-hydroxy esters via one-pot vicarious nucleophilic substitution and oxidation

Doi:10.1039/a900986h
(1999)

Article Doi