Synthesis and First Applications of a New Chiral Auxiliary (tert-Butyl 2-(tert-Butyl)-5,5-dimethyl-4-oxoimidazolidine-1-carboxylate)

Article abstract of DOI:10.1002/hlca.19950780512

Both enantiomers of tert-butyl 2(tert-butyl)-5,5-dimethyl-4-oxoimidazolidine-1-carboxylate (11; Bbdmoic) were prepared from L-alanine (Schemes 1 and 2).The parent heterocycle, 2-tert-butyl-5,5-dimethylimidazolidin-4-one (12; from 2-aminoisobutyramide, H-A