
Tetrahedron Letters p. 3143 - 3146 (1980)
Update date:2022-08-06
Topics:
Corey
Clark, David A.
Marfat, Anthony
Goto, Giichi
Syntheses are described for the "slow reacting substances" 11-trans-leukotriene C (3) (previously known as leukotriene C-2) and leukotriene D (4), the cys-gly analog of leukotriene C (2). The synthesized leukotrienes 3 and 4 were instrumental in the assignment of structure to these members of the family of naturally occuring slow reacting substances which includes also 2.
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